Nova Research Labs

Cardiac Action Potential

Cardiac action potentials allow an integrated look at the effects of a drug on ion channels important in cardiac conduction and repolarization.

  • Assays can be performed using atrial or ventricular myocytes or Purkinje fibers
  • Cells can be from guinea pig, rabbit, canine
  • Acutely isolated adult human cells available
  • Normal or diseased human cells available


  • Indicator of multi-channel effects
  • Can detect proarrhythmic markers
  • Adult human cardiac insight when human myocytes are used
  • Avoids issues of embryonic phenotype observed with iPS-CMs

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